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Diflucan - fluconazole

Diflucan online information portal.

What Is Diflucan (Fluconazole) and How It Works?

Diflucan is an antifungal medication belonging to the “azole” family of drugs. Its generic name is fluconazole, and it is related to other antifungals such as miconazole (Micatin and Monistat), clotrimazole (Lotrimin), itraconazole (Sporanox), and ketoconazole (Nizoral). These drugs work by killing harmful fungi in the body and preventing their growth. They are commonly used to treat oral thrush, esophageal and vaginal yeast infections, fungal skin infections such as ringworm, and nail infections called onychomycosis. Diflucan is often prescribed after other antifungals have been tried but failed to produce a cure, or when other antifungals cannot be used because they are not well tolerated by the person.

Candida - fungusDiflucan is also used to treat other Candida-related infections, including urinary tract infections, pneumonia, peritonitis, and cryoptococcal meningitis. Candida is a common species of fungus that causes various kinds of infections. Candida is always present in the human body, and it normally causes no illness. But when the fungus multiplies to form abnormally large colonies, this results in an infection that needs to be treated. People who have weakened immune systems are especially vulnerable to fungal infections called candidiasis. As such, their doctors at times prescribe Diflucan as a preventive medication or prophylaxis, even when there is no infection yet. This happens in cases of AIDS patients, cancer patients undergoing chemotherapy, and organ or bone marrow transplant patients—persons who all have compromised immune systems.

Diflucan tabletsDiflucan is available in tablet form, as an oral suspension, and as an injectable drug. The tablets come in 50, 100, 15 and 200 milligram dosages. The suspension form comes in 10 and 40 mg/ml dosages, while diflucan injections have a 2 mg/ml dosage. The doctor prescribes the appropriate dosage, and gives instructions on how often the medicine should be taken and for how long. It is important that the person strictly adheres to these instructions so that the drug can take optimum effect. The treatment period may last from two weeks to a few months, depending on the disease. Fungal skin infections often require treatment for two weeks, even though the symptoms may subside within a few days of taking diflucan. Systemic fungal infections that have penetrated the bloodstream, such as cryptococcal meningitis, naturally require longer treatment.

People with kidney diseases can't take Diflucan.Persons who take diflucan may or may not experience side effects. The most common side effects are stomach pain, nausea and headaches. Some people may also experience diarrhea, dizziness, an unusual taste in the mouth, allergic reactions, fever, and jaundice (yellowish discoloration of the skin). When there is jaundice, it is possible that the drug has produced an adverse effect on the liver. Fluconazole has been known to cause liver dysfunction; as such, it is not recommended for persons who have liver diseases. 

Generally, fluconazole is also not prescribed for person with heart or kidney diseases, for pregnant women, and for nursing mothers. Similarly, people who are taking diuretics, rifampin, blood thinners and other drugs are not good candidates for fluconazole treatment. The doctor must be informed of any drug the person is taking, or any existing medical condition, when seeking treatment for a fungal infection.